T-Bag (Robert Knepper) is at a Pratt, Kansas veteran’s hall. Pretending to be a veteran, T-Bag asks a veteran playing pool where to get a prosthetic hand. He tells him to go to a VA Hospital. When T-Bag says that money is no object for him, the veteran throws an orientation slur at him, while T-Bag gazes ominously.

Newly fitted with the veteran’s prosthetic hand, T-Bag stalks a United States Postal Service worker named Denise at a nearby bus stop. Following her to a diner, he charms her and finds himself in her home. He promises to meet her at work and take her to a restaurant. Upon meeting her at work, T-Bag persuades her to give her the address of his ex-girlfriend Susan Hollander (K. K. Dodds), who turned him in to America’s Most Wanted years ago. When Denise sees a wanted poster behind T-Bag with his face on it, she becomes shocked, and is killed moments later.

Susan Hollander opens the door to her new Ness City, Kansas home, not expecting to see escaped serial killer Theodore “T-Bag” Bagwell at her doorstep, just where he promised her he would be during their previous meeting in Fox River State Penitentiary.

In the meantime, Brad Bellick (Wade Williams) is at the Greeley County, Kansas district court, as the county prosecutor (Andrew Sensenig) makes his case to deny bail. The prosecutor played a recording of the threatening phone call to the murdered Roy Geary for the courtroom to hear as the judge denies bail for Bellick. Later, in a holding facility, Bellick’s public defender Greg Nagel (Bruce DuBose) tells him that there’s a good chance he will get the death penalty unless he agrees to plead guilty and receive a 25 year sentence. Bellick agrees, under the condition that he be transferred to Illinois, so he can be near his mother.

In Joliet, Illinois, the new Fox River warden Ed Pavelka is talking to the media; pledging not to make the same mistakes as his predecessor Henry Pope. He also announces his intention to swiftly execute Lincoln Burrows, while Michael Scofield will probably get life in prison for the escape.

Bellick later arrives, talking to Correctional Officer Louis Patterson (Phillip Edward Van Lear), asking him to put him in Ad Seg and to later enroll him in a work release program. Patterson replies that the CO’s no longer run the prison, and that he will be sent to the general population. His new cellmate is Avocado (Daniel Allar), who, Bellick, in his CO capacity, earlier used to punish Fox River inmate David Apolskis. The scene of Bellick being placed in General Population is reminiscent of the shot of Michael in his prison cell in the series pilot (in fact the shot is the same one used in the pilot, with Bellick’s cell pasted over Michael’s upon close inspection you can see that the inmates in adjacent cells are all in the same postions as they are in the Pilot).

Sara Tancredi (Sarah Wayne Callies) continues to try to contact Michael with no success, not knowing the fate of the brothers until she sees the news report of their recapture at an electronics store. Shocked, she alters her appearance in a public restroom by cutting her hair with a razor. Dropping her real identification in a trash bin, Sara blends into the crowd.

Fernando Sucre’s (Amaury Nolasco) plane is being chased by military jets beyond the American border into Mexico. The pilot tells him they are allowed to cross the border since 9/11 and that their only hope of survival is to escape the plane with parachutes. The pair jumps out of the plane, and lands in the Sonoran Desert. Later, Sucre glances at the dead pilot, killed on impact, before he walks away into the desert.

Michael Scofield (Wentworth Miller) and Lincoln Burrows (Dominic Purcell) are held up at gunpoint by Agent Alexander Mahone (William Fichtner) while Michael’s mobile telephone rings. Before Mahone can shoot the two brothers, the United States Border Patrol arrives. An officer tells Mahone to drop his weapon while they apprehend Michael and Lincoln.

The brothers are taken to a Las Cruces, New Mexico holding facility, where the authorities are preparing them for their return to Fox River. Agent Kim tells Mahone to kill Michael and Lincoln, but Mahone protests, stating that they are in a room filled with law enforcement officers. Kim replies by threatening Mahone’s family. As Michael’s phone vibrates in an evidence bag, the brothers discuss how they will contact Sara Tancredi. Michael asserts himself, demanding to have a phone call. The officer replies that it will have to wait until he is back at Fox River. In an adjacent room, Mahone brandishes his sidearm, briefly pointing it at himself.

Paul Kellerman (Paul Adelstein) speaks to Agent Kim (Reggie Lee), pleading for his job back. He threatens to use his information concerning Caroline Reynolds should Kim refuse. The Pad Man, a mysterious operative superior to agent Kim, writes instructions to him, telling him to switch the phone to speaker mode and to ask Kellerman what kind of plan he has in mind. Kellerman reveals a plan for an ambush of the brothers in Albuquerque, New Mexico, en route to the brothers’ trip back to Fox River, where their murder will look like an accident. Agent Kim, on the Pad Man’s instructions, later tells Mahone to kill Kellerman during the crossfire. Mahone protests, saying he is not Jack Ruby. Kim replies that Ruby acted alone, while the US Government would be behind his action.

Michael and Lincoln’s transport van is stalled in an Albuquerque tunnel by a jackknifed semi, setting up the ambush. The brothers manage to escape their transport van, as Lincoln’s shackles are left unlocked, and a guard (Kelly O’Neil Jackson), Kellerman’s alleged contact in the Illinois DOC, suspiciously leaves his keys behind. Although suspicious that the set up is too easy, Lincoln eventually convinces Michael to make a break for it, and the brothers escape through a metal door, and through a series of small tunnels, until they are caught between Kellerman and Mahone. As the brothers prepare to die, Kellerman fires his weapon at Mahone who is shot and falls. Kellerman tells both Lincoln and Michael, “President Reynolds ruined your life, she ruined my life. You want to take that bitch down? You just found your inside man, but it’s got to be right now.” Both Lincoln and Michael follow Kellerman.